pISSN : 2383-6415   eISSN : 2383-6423

Current Interventions to Improve Adherence to Immunosuppressants in Liver Transplant Recipients: a Systematic Review


PDF   


AUTHOR :
 

INFORMATION : page. 17~26 / 2016 Vol.18 No.1


ABSTRACT

Purpose: Adherence to immunosuppressants is the key to prevent organ rejection in organ transplant recipients. The purpose of this study was to investigate current interventions to improve adherence to immunosuppressants in liver transplant recipients. Methods: A systemic literature search was done using PubMed, Embase, Cochrane Library, CINAHL and four Korean databases to identify experimental studies reported in English or Korean up to and including 2015. We identified eight intervention studies on the adherence to immunosuppressants in liver transplant recipients independently reviewed by two reviewers. The quality and risk of bias of the selected studies were assessed. Results: Education, conversion of regimen, and text messaging were identified as intervention techniques to improve adherence. We found positive results in three out of four studies implementing educational strategies, but the results were not sufficient to draw a definite conclusion. Conversion from a twice-daily tacrolimus-based regimen to a once-daily tacrolimus extended-release formula was used in three adult-only studies and its effectiveness was confirmed. One study showed that improved adherence and outcomes were effected by using text messaging with pediatric patients. Conclusion: Future research is needed to facilitate interventions to improve adherence to immunosuppressants in various ages of patients including pediatric/adolescent liver transplant recipients.

Keyword :

transplant recipients,Immunosuppressant,Adherence,Systematic review,간이식 환자,면역억제제,복용이행,체계적 문헌고찰


CONTENT

Journal Archive

19 Volumes, 4 Issues, 433 Articles








show all


Tag Cloud

Bacteria triglyceride 유전학 교육과정 현황 HPA axis 활력증후 식이 섭취량

Korean Society of Biological Nursing Science (Stay Connected)
Department of Clinical Nursing, University of Ulsan, 88, Olympic-ro 43-gil, Songpa-gu, Seoul, KR 05505, Republic of Korea
Tel : +82-2-3010-5311 (Contact JKBNS Customer care: bionursing@naver.com) http://www.bionursing.or.kr/
Copyright JKBNS. All Rights Reserved.
Design by Hakjisa Pub.